![]() ![]() Across 213 matched pairs, multivariable HR for death/transplant associated with PPMv was 3.8 (95%CI 1.9-7.6 P< 0.001). ![]() Median percent ventricular pacing (Vp) was 90.8% (25th-75th percentile: 4.3%-100%) in the PPMv cohort. ![]() Median age at enrollment was 5.3 years (quartiles: 1.5-13.2 years), follow-up 6.9 years (3.4-11.6 years). Primary outcome was transplantation or death.RESULTS: In total, 236 PPMv subjects and 213 matched controls were identified (22 centers, 9 countries). Controls were matched 1:1 to PPMv subjects by ventricular morphology and sex, identified within center, and enrolled at matched age. Centers contributed baseline and longitudinal data for functionally SV patients with PPMv. Previous studies have identified that the need for a permanent ventricular pacing system (PPMv) may be associated with additional adverse long-term outcomes.OBJECTIVES: The goal of this study was to quantify the attributable risk of PPMv in patients with SV, and to identify modifiable risk factors.METHODS: This international study was sponsored by the Pediatric and Congenital Electrophysiology Society. BACKGROUND: Palliation of the single ventricle (SV) circulation is associated with a burden of lifelong complications. ![]()
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